A cytosolic heat shock protein 90 and co-chaperone p23 complex activates RIPK3/MLKL during necroptosis of endothelial cells in acute respiratory distress syndrome
Xiufeng Yu, Min Mao, Xia Liu, Tingting Shen, Tingting Li, Hao Yu, Junting Zhang, Xinxin Chen, Xijuan Zhao, Daling Zhu
Topics & Concepts
NecroptosisARDSRIPK1FADDCell biologyProgrammed cell deathDeath domainBiologyCancer researchMedicineImmunologyApoptosisCaspaseLungInternal medicineBiochemistryCell death mechanisms and regulationInflammasome and immune disordersSepsis Diagnosis and Treatment