Combined antitumor effects of anti-EGFR variant III CAR-T cell therapy and PD-1 checkpoint blockade on glioblastoma in mouse model
Yujie Song, Qingtian Liu, Tong Zuo, Guoyan Wei, Shunchang Jiao
Topics & Concepts
BlockadeChimeric antigen receptorCancer researchGlioblastomaTumor microenvironmentImmune checkpointT cellCAR T-cell therapyCytotoxic T cellPotencyNeoplasmIn vitroBiologyImmunologyMedicineReceptorImmune systemTumor cellsInternal medicinePathologyBiochemistryCAR-T cell therapy researchCancer Immunotherapy and BiomarkersImmunotherapy and Immune Responses