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STING mediates lysosomal quality control and recovery through its proton channel function and TFEB activation in lysosomal storage disorders

Zhen Tang, Cong Xing, Antonina M. Araszkiewicz, Kun Yang, Wanwan Huai, Devon Jeltema, Nicole Dobbs, Yihe Zhang, Lu Sun, Nan Yan

2025Molecular Cell31 citationsDOIOpen Access PDF

Topics & Concepts

BiologyTFEBCell biologyFunction (biology)LysosomeLysosomal storage disordersBiochemistryEnzymeMosquito-borne diseases and controlCalcium signaling and nucleotide metabolismToxoplasma gondii Research Studies
STING mediates lysosomal quality control and recovery through its proton channel function and TFEB activation in lysosomal storage disorders | Litcius