Exosomal miR-1246 and miR-155 as predictive and prognostic biomarkers for trastuzumab-based therapy resistance in HER2-positive breast cancer
Zhen Zhang, Luoyan Zhang, Guoxiang Yu, Zhigang Sun, Tiantian Wang, Xingsong Tian, Xuening Duan, Chi Zhang
Topics & Concepts
TrastuzumabOncologyMedicineInternal medicineReceiver operating characteristicBreast cancerProportional hazards modelStage (stratigraphy)CancermicroRNALogistic regressionSurvival analysisArea under the curveBiomarkerBiologyGenePaleontologyBiochemistryExtracellular vesicles in diseaseHER2/EGFR in Cancer ResearchProtease and Inhibitor Mechanisms