Stereoselective Access to Highly Substituted Vinyl Ethers via <i>trans</i> -Difunctionalization of Alkynes with Alcohols and Iodine(III) Electrophile
Wei Ding, Jinkui Chai, Chen Wang, Junliang Wu, Naohiko Yoshikai
Abstract
-iodanyl vinyl ethers in good yields with high regio- and stereoselectivities. The benziodoxole moiety of the products can be used as a versatile linchpin for the synthesis of structurally diverse vinyl ethers that are difficult to access by other means.
Topics & Concepts
ChemistryElectrophileStereoselectivityMoietyTrifluoromethanesulfonateOrganic chemistryIodineCombinatorial chemistryCatalysisOxidative Organic Chemistry ReactionsCatalytic C–H Functionalization MethodsVanadium and Halogenation Chemistry