Development of isatin-functionalized benzenesulfonamides as novel carbonic anhydrase II and VII inhibitors with antiepileptic potential
Wagdy M. Eldehna, Anwar A El-Hamaky, Simone Giovannuzzi, Zainab M. Elsayed, Mahmoud Abdelrahman Alkabbani, Eman F. Khaleel, Mohammad M. Al‐Sanea, Mahmoud F. Abo-Ashour, Yosra S.R. Elnaggar, Alessio Nocentini, Claudiu T. Supuran, Haytham O. Tawfik
Topics & Concepts
ChemistryAnticonvulsantCarbonic anhydraseIsatinPharmacologyValproic AcidPilocarpineLamotrigineEpilepsyBiochemistryEnzymeNeuroscienceMedicineBiologyOrganic chemistryEnzyme function and inhibitionSynthesis and Catalytic ReactionsCholinesterase and Neurodegenerative Diseases