Visible-Light-Induced Meerwein Fluoroarylation of Styrenes
Haijun Tang, Bin Zhang, Fei Xue, Chao Feng
Abstract
An unprecedented approach for assembling a broad range of 1,2-diarylethane derivatives with fluorine-containing fully substituted carbon centers was developed. The protocol features straightforward operation, proceeds under metal-free condition, and accommodates a large variety of synthetically useful functionalities. The critical aspect to the success of this novel transformation lies in using aryldiazonium salts as both aryl radical progenitor and also as single electron acceptor which elegantly enables a radical-polar crossover manifold.
Topics & Concepts
ChemistryAryl radicalArylFluorinePolarAcceptorCombinatorial chemistryCarbon fibersNanotechnologyPhotochemistryOrganic chemistryAlkylComputer scienceAlgorithmComposite numberMaterials sciencePhysicsCondensed matter physicsAstronomyFluorine in Organic ChemistryRadical Photochemical ReactionsCatalytic C–H Functionalization Methods