DNA/HSA binding and anticancer properties of pendant acetate bearing mono-nuclear Ni(<scp>ii</scp>) and bridging acetate bearing di-nuclear Cu(<scp>ii</scp>) Schiff base complexes: an experimental and molecular docking study
Biman Ari, Manik Das, Paula Brandão, Somali Mukherjee, Atish Dipankar Jana, Biplab Koley, Soumik Laha, Md. Maidul Islam, Indranil Choudhuri, Nandan Bhattacharya, Bidhan Chandra Samanta, Nitin Chattopadhyay, Tithi Maity
Abstract
Investigation of one pendant acetate bearing a mononuclear Ni( ii ) complex (1) and bridging acetate bearing a dinuclear Cu( ii ) complex (2) with respect to their DNA/HSA binding efficacy along with their apoptotic induced anticancer properties.
Topics & Concepts
ChemistryBearing (navigation)Bridging (networking)DNASchiff baseEthyl acetatePolymer chemistryNuclear chemistryStereochemistryOrganic chemistryBiochemistryComputer networkCartographyGeographyComputer scienceMetal complexes synthesis and propertiesSynthesis and Characterization of Heterocyclic CompoundsClick Chemistry and Applications