Self-assembling peptide hydrogels functionalized with LN- and BDNF- mimicking epitopes synergistically enhance peripheral nerve regeneration
Shuhui Yang, Chong Wang, Jinjin Zhu, Changfeng Lu, Haitao Li, Fuyu Chen, Jiajü Lü, Zhe Zhang, Xiaoqing Yan, He Zhao, Xiaodan Sun, Lingyun Zhao, Jing Liang, Yu Wang, Jiang Peng, Xiumei Wang
Abstract
. The results demonstrated the synergistic effect of IKVAV and RGI on axonal regrowth and function recovery after peripheral nerve injury.
Topics & Concepts
Self-healing hydrogelsNanofiberExtracellular matrixLamininBiophysicsNeurotrophinBasement membraneChemistryRegeneration (biology)Cell biologyCiliary neurotrophic factorSelf-assembling peptideNeurotrophic factorsMaterials scienceBiochemistryNanotechnologyBiologyPolymer chemistryReceptorNerve injury and regenerationSupramolecular Self-Assembly in MaterialsRNA Interference and Gene Delivery