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Palladium-catalyzed Heck cyclization/allylation with homoallyl alcohols<i>via</i>retro-allylation

Ping‐Xin Zhou, Xiaozhe Yang, Xueyan Du, Shujie Zhao, Han Wang, Xinguang Li, Ning Liu, Xinqiang Tan, Feng Ren, Yong‐Min Liang

2022Organic Chemistry Frontiers14 citationsDOI

Abstract

A palladium-catalyzed reaction of aryl iodide-tethered alkenes with homoallyl alcohols is reported, providing a convenient and efficient approach to C(sp 3 )–allylation products.

Topics & Concepts

ChemistryPalladiumCatalysisArylIodideHeck reactionOrganic chemistryMedicinal chemistryCombinatorial chemistryAlkylCatalytic C–H Functionalization MethodsCatalytic Cross-Coupling ReactionsCatalytic Alkyne Reactions
Palladium-catalyzed Heck cyclization/allylation with homoallyl alcohols<i>via</i>retro-allylation | Litcius