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The Advent of Generative Chemistry

Quentin Vanhaelen, Yen‐Chu Lin, Alex Zhavoronkov

2020ACS Medicinal Chemistry Letters151 citationsDOIOpen Access PDF

Abstract

molecular design. Those techniques aim at a more efficient use of the data and a better exploration of the chemical space. We review recent advances for the generation of novel molecules with desired properties with a focus on the applications of GANs, RL, and related techniques. We also discuss the current limitations and challenges in the new growing field of generative chemistry.

Topics & Concepts

Generative grammarComputer scienceChemical spaceAdversarial systemBridging (networking)Artificial intelligenceReinforcement learningData scienceCognitive scienceChemistryDrug discoveryPsychologyBiochemistryComputer networkComputational Drug Discovery MethodsMachine Learning in Materials ScienceInnovative Microfluidic and Catalytic Techniques Innovation
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