Impact of intraventricular septal fiber orientation on cardiac electromechanical function
Jairo Rodríguez Padilla, Argyrios Petras, Julie Magat, Jason D. Bayer, Yann Bihan-Poudec, Dounia El Hamrani, Girish Ramlugun, Aurel Neic, Christoph M. Augustin, Fanny Vaillant, Marion Constantin, David Benoîst, Line Pourtau, Virginie Dubes, Julien Rogier, Louis Labrousse, Olivier Bernus, Bruno Quesson, Michel Haı̈ssaguerre, Matthias A. F. Gsell, Gernot Plank, Valéry Ozenne, Edward J. Vigmond
Abstract
A dual-layer organization of the fiber orientation in the intraventricular septum was identified in ex vivo hearts of large mammals. The RV septum has a downwardly directed superficial layer that is continuous with the moderator band. Electrically, it produced a diamond activation pattern. Electromechanically, little change in pressure volume loops were noticed but stress distribution was altered. Fiber distribution derived from diffusion tensor imaging should be considered for an accurate strain and stress analysis.