H3K27 acetylation-induced FSTL1 upregulation by P300/RUNX1 co-activation exacerbated autophagy-mediated neuronal damage and NF-κB-stimulated inflammation in Alzheimer’s disease
Dongmei Dai, Junzheng Xie, Yun Zheng, Fangbin Chen, Bin Zhao, Miao Li
Topics & Concepts
Downregulation and upregulationAutophagyGene knockdownInflammationNF-κBPathogenesisAcetylationCell biologyActivator (genetics)Cancer researchChemistryImmunologyBiologyMedicineApoptosisReceptorBiochemistryGeneKruppel-like factors researchEndoplasmic Reticulum Stress and DiseaseAutophagy in Disease and Therapy