Asymmetric Organocatalysis in Deep Eutectic Solvents
Diego A. Alonso, Sarah‐Jayne Burlingham, Rafael Chinchílla, Gabriela Guillena, Diego J. Ramón, M. TIECCO
Abstract
Abstract The recent advances in asymmetric organocatalysis using eutectic mixtures as a reaction medium are revised in this mini‐review. In addition, the first enantioselective transformations using chiral eutectic solvents, which play the role of a green medium and organocatalyst, are described. In this minireview we intend to deepen not only in the synthetic aspects of asymmetric organocatalysis in eutectic mixtures, but also in the fundamental issues that seem to be essential for a successful development of this promising, and at the same time challenging, methodology.
Topics & Concepts
OrganocatalysisEnantioselective synthesisEutectic systemChemistryOrganic chemistryCombinatorial chemistryBiochemical engineeringCatalysisAlloyEngineeringIonic liquids properties and applicationsAsymmetric Synthesis and CatalysisAlkaloids: synthesis and pharmacology