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Lattice Hydrogen Engineering Unlocks Inert TiO <sub>2</sub> for H <sub>2</sub> O <sub>2</sub> Electrosynthesis in Neutral Media

Nannan Hou, Ke Ye, Mingzhou Wang, Jun Wang, Zhixiang She, Junsheng Song, Jiankang Zheng, Guozhen Zhang, Yu Zhou, Haitao Liu, Qing Zhu, Yang Mu

2025Angewandte Chemie5 citationsDOI

Abstract

Abstract Electrochemical H 2 O 2 production through the two‐electron oxygen reduction reaction (2e − ORR) represents a transformative route for sustainable and decentralized chemical synthesis. Nevertheless, conventional catalysts struggle to achieve optimal intermediates adsorption and efficient proton‐coupled electron transfer (PCET) under neutral conditions, as the sluggish dissociation of water imposes a severe kinetic bottleneck. Herein, we introduce a lattice hydrogen engineering strategy that confers unprecedented catalytic functionality to traditionally inert metal oxides. Through precise hydrogen implantation into the TiO 2 lattice, we establish Ti‐O 2C ‐H active centers—a dual‐function motif that simultaneously achieves near‐ideal OOH* adsorption (positioned at the Sabatier volcano apex) and intrinsic proton reservoir capability. This atomically engineered H‐TiO 2 catalyst delivers &gt; 95% H 2 O 2 selectivity, operating stably for over 100 h at an industrial current density of 200 mA cm −2 . This robust operation yields a high H 2 O 2 production rate of 13,968 mmol g −1 h −1 with an energy efficiency of 41.3%. Crucially, the universality of lattice hydrogen engineering is demonstrated through the activation of WO 3 , MoO 3 , and Nb 2 O 5 , yielding comparable performance enhancements for neutral 2e − ORR. By unlocking metal oxides as a robust catalyst platform for H 2 O 2 electrosynthesis, this work establishes a scalable pathway toward scalable, green and cost‐effective peroxide production.

Topics & Concepts

CatalysisHydrogenElectrosynthesisHydrogen productionAdsorptionElectrochemistryWater splittingDissociation (chemistry)ChemistryMetalChemical engineeringMaterials scienceInorganic chemistryOxygenPhotochemistryInertHeterogeneous catalysisHydrogen peroxideRedoxRate-determining stepElectron transferAmmonia productionRadicalInert gasNanotechnologyActive siteMetal-organic frameworkHeterolysisChemical physicsReversible hydrogen electrodeElectrocatalysts for Energy ConversionAdvanced battery technologies researchMetalloenzymes and iron-sulfur proteins
Lattice Hydrogen Engineering Unlocks Inert TiO <sub>2</sub> for H <sub>2</sub> O <sub>2</sub> Electrosynthesis in Neutral Media | Litcius