<i>CXCL10</i> potentiates immune checkpoint blockade therapy in homologous recombination-deficient tumors
Zhiwen Shi, Jianfeng Shen, Junjun Qiu, Qingguo Zhao, Keqin Hua, Hongyan Wang
Abstract
is associated with HRD but also introduced a potential new perspective for identifying prognostic biomarkers of immunotherapy.
Topics & Concepts
Immune checkpointBreast cancerImmunotherapyTranscriptomeTumor microenvironmentCXCL10Immune systemBiomarkerMedicineCancer immunotherapyCancer researchOncologyCancerBiologyImmunologyGeneInternal medicineGene expressionChemokineGeneticsCancer Immunotherapy and Biomarkersinterferon and immune responsesFerroptosis and cancer prognosis