Switching of C–C and C–N Coupling/Cleavage for Hypersensitive Detection of Cu<sup>2+</sup> by a Catalytically Mediated 2-Aminoimidazolyl-Tailored Six-Membered Rhodamine Probe
Linlin Yang, A-Ling Tang, Peiyi Wang, Song Yang
Abstract
A robust six-membered rhodamine spirocyclic probe 1 containing a versatile 2-aminoimidazolyl moiety was elaborately designed and synthesized via an attractive C–C and C–N coupling strategy to improve the performance in the detection of ultralow transition metal ions. Probe 1 allowed the highly hypersensitive detection of Cu2+ with a superior picomolar limit of detection (35 pM) and nanomolar naked-eye performance (80 nM) via the switching of C–C and C–N cleavage by a catalytic hydrolysis mode.
Topics & Concepts
ChemistryMoietyCleavage (geology)Detection limitRhodamineIonMetal ions in aqueous solutionCatalysisCoupling (piping)Naked eyeHydrolysisPhotochemistryAnalytical Chemistry (journal)StereochemistryFluorescenceChromatographyOrganic chemistryMaterials scienceOpticsPhysicsComposite materialMetallurgyFracture (geology)Molecular Sensors and Ion DetectionLuminescence and Fluorescent MaterialsAdvanced biosensing and bioanalysis techniques