Litcius/Paper detail

Clinical characteristics, risk factors, and cardiac manifestations of cancer patients with COVID-19

Yan Huang, Zhenhong Hu, Dong Hu, Zhou Quan, Xiaoyang Zhou, Guohua Fan, Xiu Chen, Xiaoxiong Liu, Zhonghe Zhang, Ganxiao Chen, Yanwen Wu, Fangqi Zhang, Congzheng Mao, Hao Xia, Jinjun Liang, Bo Yang, Hong Jiang, Congxin Huang, Héctor Barajas-Martínez, Dan Hu

2021Journal of Applied Physiology13 citationsDOIOpen Access PDF

Abstract

Our study indicates that the 30-day mortality is higher in COVID-19 patients with cancer; more COVID-19 patients with cancer are in severe and critical status; age, respiratory rate, neutrophil count, AST, BUN, MYO, Pro-BNP, disease severity status, underlying diseases, and fever are risk factors for in-hospital mortality among COVID-19 cancer cases; COVID-19 patients with cancer display severely impaired myocardium, damaged heart function, and imbalanced homeostasis of coagulation; what is more, those with both cancer and CVD have more significantly increased Pro-BNP and D-Dimer level.

Topics & Concepts

MedicineCoronavirus disease 2019 (COVID-19)2019-20 coronavirus outbreakCancerSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Internal medicineCardiologyIntensive care medicinePathologyDiseaseOutbreakInfectious disease (medical specialty)COVID-19 and healthcare impactsCOVID-19 Clinical Research StudiesChemotherapy-induced cardiotoxicity and mitigation