Uncovering New Excited State Photochemical Reactivity by Altering the Course of the De Mayo Reaction
Sunil Kumar Kandappa, Lakshmy Kannadi Valloli, Steffen Jockusch, Jayaraman Sivaguru
Abstract
An unprecedented and previously unknown photochemical reactivity of 1,3-dicarbonyl compounds is observed with amino-alkenes leading to dihydropyrans. This novel photochemical reactivity changes the established paradigm related to the De Mayo reaction between 1,3-dicarbonyl compounds and alkenes. This new reaction allows convenient access to the Marmycin core in a single step from commercially available reactants. The origin and scope of this new photoreaction is detailed with preliminary photophysical and mechanistic investigations.
Topics & Concepts
ChemistryReactivity (psychology)PhotochemistryExcited stateAlternative medicinePhysicsNuclear physicsMedicinePathologyRadical Photochemical ReactionsFluorine in Organic ChemistryOxidative Organic Chemistry Reactions