A Small Molecule that Binds an RNA Repeat Expansion Stimulates Its Decay via the Exosome Complex
Alicia J. Angelbello, Raphael I. Benhamou, Suzanne G. Rzuczek, Shruti Choudhary, Zhenzhi Tang, Jonathan L. Chen, Madhuparna Roy, Kye Won Wang, Ilyas Yildirim, Albert S. Jun, Charles A. Thornton, Matthew D. Disney
Topics & Concepts
RNAMyotonic dystrophyIntronUntranslated regionBiologyCell biologyMessenger RNAExoribonucleaseRNA-binding proteinNucleic acid structureExosome complexSmall moleculeMolecular biologyChemistryNon-coding RNAGeneticsGeneRNase PRNA Research and SplicingGenetic Neurodegenerative DiseasesMitochondrial Function and Pathology