Elevated clozapine levels and toxic effects after SARS-CoV-2 vaccination
Deborah Thompson, Clay M. Delorme, Randall F. White, William G. Honer
Abstract
Case studies indicate that coronavirus disease 2019 (COVID-19) can be associated with toxic clozapine levels, requiring monitoring to maintain therapeutic levels and prevent relapses of psychosis. [1][1]–[4][2] High clozapine levels are consistent with infection-related inflammation inhibiting
Topics & Concepts
ClozapineCoronavirus disease 2019 (COVID-19)PsychosisMedicineSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)2019-20 coronavirus outbreakCoronavirusDiseaseInflammationSchizophrenia (object-oriented programming)ImmunologyPharmacologyVirologyPsychiatryInternal medicineOutbreakInfectious disease (medical specialty)Tryptophan and brain disordersLong-Term Effects of COVID-19Pharmacological Receptor Mechanisms and Effects