Design, synthesis, and biological evaluation of furosemide analogs as therapeutics for the proteopathy and immunopathy of Alzheimer's disease
Zhiyu Wang, Yanfei Wang, Jagadeesh Prasad Pasangulapati, Kurt R. Stover, Xiaojing Liu, Stephanie Schier, Donald F. Weaver
Topics & Concepts
NeuroinflammationChemistryMicrogliaProinflammatory cytokineDownregulation and upregulationPharmacologyFurosemideNitric oxideNeuroprotectionCell biologyBiochemistryInflammationImmunologyBiologyGeneOrganic chemistryAlzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration MechanismsCholinesterase and Neurodegenerative Diseases