Targeting the interplay between MMP-2, CA II and VEGFR-2 via new sulfonamide-tethered isomeric triazole hybrids; Microwave-assisted synthesis, computational studies and evaluation
Mohamed Reda Aouad, Meshal A. Almehmadi, Fawzia Faleh Albelwi, Mohamed Teleb, Gina N. Tageldin, Marwa M. Abu‐Serie, Mohamed Hagar, Nadjet Rezki
Topics & Concepts
ChemistryPharmacophoreDruggabilityClick chemistryTriazoleSulfonamideCancer cellCancer researchStereochemistryCombinatorial chemistryBiochemistryCancerBiologyOrganic chemistryGeneticsGenePeptidase Inhibition and AnalysisClick Chemistry and ApplicationsProtease and Inhibitor Mechanisms