Design and novel synthetic approach supported with molecular docking and biological evidence for naphthoquinone-hydrazinotriazolothiadiazine analogs as potential anticancer inhibiting topoisomerase-IIB
Samy Mohamady, Abdullah Ahmed Gibriel, Mahmoud S. Ahmed, Moataz S. Hendy, Bassem H. Naguib
Topics & Concepts
ChemistryCytotoxicityTopoisomeraseNaphthoquinoneDocking (animal)StereochemistryMoietyApoptosisIn vitroCombinatorial chemistryBiochemistryOrganic chemistryNursingMedicineCancer therapeutics and mechanismsBioactive Compounds and Antitumor AgentsSynthesis and biological activity