VEGFR-2 inhibiting effect and molecular modeling of newly synthesized coumarin derivatives as anti-breast cancer agents
Eman Y. Ahmed, Nehad A. Abdel Latif, Mohamed F. El‐Mansy, Weam Salah Goda Elserwy, Omaima M. Abdelhafez
Topics & Concepts
ChemistryStaurosporineCytotoxicityCoumarinIC50In vitroADMEKinaseStereochemistryMCF-7Cytotoxic T cellDocking (animal)Lipinski's rule of fiveCancer cellBiochemistryPharmacologyIn silicoCancerProtein kinase ABiologyNursingGeneticsMedicineOrganic chemistryHuman breastGeneSynthesis and biological activityBioactive Compounds and Antitumor AgentsAngiogenesis and VEGF in Cancer