Inhibition of Drp1-mediated mitochondrial fission improves contrast-induced acute kidney injury by targeting the mROS-TXNIP-NLRP3 inflammasome axis
Jiong Zhang, Qian Wei, Shukun Wu, Fang Wang, Tong-ling Yuan, Jia Wang, Jia Wang
Topics & Concepts
TXNIPMitochondrial fissionInflammasomeDNM1LPharmacologyOxidative stressMitochondrionBiologyChemistryMedicineCell biologyBiochemistryThioredoxinReceptorAcute Kidney Injury ResearchInflammasome and immune disordersLiver Disease and Transplantation