Pd-catalyzed direct functionalization of glycals with cycloalkenones: application to the synthesis of chiral phenanthrenones
Mittali Maheshwari, Ram Pratap Pandey, Nazar Hussain
Abstract
A palladium-catalyzed direct C–H functionalization of glycals with cycloalkenones is described and a series of C-2 functionalized glycals were synthesized efficiently with cyclic enones.The synthesised products were further transformed into chiral phenanthrenones.
Topics & Concepts
ChemistrySurface modificationPyranCycloadditionCatalysisEnantioselective synthesisCombinatorial chemistryPalladiumOrganic chemistryPhysical chemistryCarbohydrate Chemistry and SynthesisSynthesis and Biological ActivityFluorine in Organic Chemistry