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KSHV infection drives poorly cytotoxic CD56-negative natural killer cell differentiation in vivo upon KSHV/EBV dual infection

Nicole Caduff, Donal McHugh, Lisa Rieble, Catherine S. Forconi, John Michael Ong’echa, Peter O. Oluoch, Ana Raykova, Anita Murer, Michelle Böni, Lara Zuppiger, Thomas F. Schulz, David J. Blackbourn, Obinna Chijioke, Ann M. Moormann, Christian Münz

2021Cell Reports37 citationsDOIOpen Access PDF

Abstract

NK cell differentiation.

Topics & Concepts

BiologyNatural killer cellCytotoxic T cellVirologyImmune systemImmunologyAntibody-dependent cell-mediated cytotoxicityHuman cytomegalovirusLymphokine-activated killer cellNK-92Interleukin 21CD16CD8VirusAntibodyCD3In vitroMonoclonal antibodyBiochemistryViral-associated cancers and disordersImmune Cell Function and InteractionCytomegalovirus and herpesvirus research
KSHV infection drives poorly cytotoxic CD56-negative natural killer cell differentiation in vivo upon KSHV/EBV dual infection | Litcius