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Reduction of DNMT3a and RORA in the nucleus accumbens plays a causal role in post-traumatic stress disorder-like behavior: reversal by combinatorial epigenetic therapy

Gal Warhaftig, Noa Zifman, Chaya Mushka Sokolik, Renaud Massart, Orshay Gabay, Daniel M. Sapozhnikov, Farida Vaisheva, Yehuda Lictenstein, Noa Confortti, Hadas Levi Ahdoot, Avi Jacob, Tzofnat Bareli, Moshe Szyf, Gal Yadid

2021Molecular Psychiatry12 citationsDOI

Topics & Concepts

EpigeneticsRetinoic acid receptorNucleus accumbensDNA methylationRetinoic acidMethylationMethyltransferaseBiologyGeneticsReceptorGeneGene expressionEpigenetics and DNA MethylationPrenatal Substance Exposure EffectsBirth, Development, and Health
Reduction of DNMT3a and RORA in the nucleus accumbens plays a causal role in post-traumatic stress disorder-like behavior: reversal by combinatorial epigenetic therapy | Litcius