Dehydrocostus lactone inhibits the proliferation of esophageal cancer cells in vivo and in vitro through ROS-mediated apoptosis and autophagy
Peng Yu, Tongxi Zhou, Sisi Wang, Yerlan Bahetjan, Xiaojun Li, Xinzhou Yang
Topics & Concepts
AutophagyApoptosisIn vivoPI3K/AKT/mTOR pathwayChemistryReactive oxygen speciesProtein kinase BIn vitroWestern blotCancer cellCancer researchPharmacologyCell biologyCancerBiochemistryBiologyBiotechnologyGeneGeneticsAutophagy in Disease and TherapyNF-κB Signaling PathwaysCell death mechanisms and regulation