Expanding the PET radioisotope universe utilizing solid targets on small medical cyclotrons
Krystle George, S. Borjian, Michael Cross, Justin W. Hicks, Paul Schaffer, Michael S. Kovacs
Abstract
), well-elucidated chemistry, and a feasible production framework. However, longer-lived radioisotopes have surged in popularity given recent regulatory approvals and incorporation of radiopharmaceuticals into patient management within the medical community. This review focuses on the applications, nuclear properties, and production and purification methods for some of the most frequently used/emerging positron-emitting, solid-target-produced radioisotopes that can be manufactured using small-to-medium size cyclotrons (≤24 MeV).
Topics & Concepts
CyclotronRadiochemistryEnvironmental scienceMedical physicsPhysicsNuclear engineeringNuclear physicsChemistryEngineeringPlasmaRadiopharmaceutical Chemistry and ApplicationsBoron Compounds in ChemistryAtomic and Subatomic Physics Research