Pharmacomodulations of the benzoyl-thiosemicarbazide scaffold reveal antimicrobial agents targeting d-alanyl-d-alanine ligase in bacterio
Alice Ameryckx, Lionel Pochet, Gang Wang, Esra Yıldız, Bouazza Es Saadi, Johan Wouters, Françoise Van Bambeke, Raphaël Frédérick
Topics & Concepts
ChemistryAntimicrobialSemicarbazoneDNA ligasePeptidoglycanStereochemistryPotencyIn vitroBiochemistryEnzymeOrganic chemistryClick Chemistry and ApplicationsCancer therapeutics and mechanismsSynthesis and Characterization of Heterocyclic Compounds