Significant anti-inflammatory aziridine-containing indole alkaloids from the Chinese medicinal plant <i>Alstonia scholaris</i>
Bin‐Yuan Hu, Yun‐Li Zhao, Zhong-Shun Zhou, Yan-Yan Zhu, Xiao‐Dong Luo
Abstract
Alstolactines D (1) and E (2), two unprecedented indole alkaloids with an aziridine scaffold, exhibited significant anti-inflammatory bioactivity.
Topics & Concepts
AziridineIndole testApocynaceaeChemistryTraditional medicineStereochemistryMedicineOrganic chemistryRing (chemistry)Alkaloids: synthesis and pharmacologySynthesis and Catalytic ReactionsTraditional and Medicinal Uses of Annonaceae