SARS-CoV-2 infection in a patient on chronic hydroxychloroquine therapy: Implications for prophylaxis
Khalid M Dousa, Sharad Malavade, Jennifer Furin, Barbara Gripshover, Marjorie Hatszegi, Leila S Hojat, Elie Saade, Robert A. Salata
Abstract
People exposed to COVID-19 have a risk of developing disease, and health care workers are at risk at a time when they are badly needed during a health care crisis. Hydroxychloroquine and chloroquine have been used as treatment and are being considered as prophylaxis. Our patient developed COVID-19 while on hydroxychloroquine and although more work is needed, this calls into question the role of these medications as preventive therapy.
Topics & Concepts
HydroxychloroquineMedicineChloroquineIntensive care medicineCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Health carePandemicDiseasePre-exposure prophylaxisFamily medicineInfectious disease (medical specialty)Internal medicineMalariaImmunologyHuman immunodeficiency virus (HIV)EconomicsEconomic growthMen who have sex with menSyphilisCOVID-19 Clinical Research StudiesLong-Term Effects of COVID-19Vitamin C and Antioxidants Research