Disrupting flight increases sleep and identifies a novel sleep-promoting pathway in <i>Drosophila</i>
Krishna Melnattur, B. Zhang, Paul J. Shaw
Abstract
) that link wing expansion and sleep. Disrupting flight activates these sleep-promoting projection neurons, as indicated by increased cytosolic calcium levels, and stably increases the number of synapses in their axonal projections. These data reveal an unexpected role for flight in regulating sleep and provide new insight into how sensory processing controls sleep need.
Topics & Concepts
Sleep (system call)Drosophila (subgenus)NeuroscienceDrosophila melanogasterBiologyGeneticsComputer scienceGeneOperating systemNeurobiology and Insect Physiology ResearchCircadian rhythm and melatoninSleep and Wakefulness Research