Role of ancillary ligands in <i>S</i> -nitrosothiol and NO generation from nitrite–thiol interactions at mononuclear zinc( <scp>ii</scp> ) sites
Balakrishnan S. Anju, Neeraja Nair, Janavi Rajput, Jeffery A. Bertke, Bhaskar Mondal, Subrata Kundu
Abstract
Thiol–nitrite interactions at systematically tuned zinc( ii ) sites illustrate that the availability of a hemilabile site for the Lewis-acidic activation of thiol governs the intramolecular proton-transfer, providing S -nitrosothiol via nitrous acid.
Topics & Concepts
ThiolZincNitriteChemistryBiochemistryOrganic chemistryNitrateNitric Oxide and Endothelin EffectsSulfur Compounds in BiologyMolecular Sensors and Ion Detection