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Randomized comparison of AI enhanced 3D printing and traditional simulations in hepatobiliary surgery

Linqian Li, Shujie Cheng, Jinghua Li, Jihong Yang, Hongguang Wang, Bin Dong, Xiaoping Yin, Hongyun Shi, Shuo Gao, Feng Gu, Zhe Han, Zhi Chen, Jisen Zhao, Quan Zhang, Jie-Zhi Cheng, Yuan Wang, Fengwei Tan, Ke Zhang

2025npj Digital Medicine15 citationsDOIOpen Access PDF

Abstract

We employed a three-phase approach, culminating in a randomized controlled trial, to assess the efficacy of 3D-printed liver models in hepatobiliary surgical planning. Phase one involved developing and selecting 35 optimal 3DP models based on timeliness, cost, precision, and alignment with digital simulations. Phase two utilized deep learning algorithms to optimize the 3D reconstruction process, significantly enhancing efficiency and accuracy compared to manual segmentation. In phase three, a randomized controlled trial with 64 patients compared surgical outcomes between those planned with AI-enhanced physical 3DP models and those with traditional digital simulations. Results demonstrated that 3DP models were produced rapidly (3.52 h at $152 each) with high precision, AI-assisted reconstruction reduced processing time (303.5 vs. 557 min), and patients using AI-enhanced physical 3DP models experienced less intraoperative blood loss. Integrating deep learning with 3D printing offers a cost-effective, scalable method to enhance surgical planning and outcomes in hepatobiliary surgery.

Topics & Concepts

Randomized controlled trialMedicineSurgeryGeneral surgeryAnatomy and Medical TechnologyRadiomics and Machine Learning in Medical ImagingSurgical Simulation and Training
Randomized comparison of AI enhanced 3D printing and traditional simulations in hepatobiliary surgery | Litcius