Stress response decay with aging visualized using a dual-channel logic-based fluorescent probe
Jingye Tian, Donglei Shi, Yanhui Zhang, Xiaokang Li, Xinming Li, Hao Teng, Tony D. James, Jian Li, Yuan Guo
Abstract
Rather than tracking aging using the resting state, ROKS, an optical probe, was developed for evaluating the degree of aging dynamically by precisely monitoring the stress response of individuals under stress.
Topics & Concepts
ThiophenolFluorescenceProto-oncogene tyrosine-protein kinase SrcCaenorhabditis elegansStressorBiophysicsChemistryCell biologyBiologyKinaseNeuroscienceBiochemistryMedicinal chemistryPhysicsQuantum mechanicsGeneGenetics, Aging, and Longevity in Model OrganismsCircadian rhythm and melatoninPhotoreceptor and optogenetics research