Synthetic routes to bicyclo[1.1.1]pentylamines: booming toolkits for drug design
Zhiyou Yu, Lei Shi
Abstract
With the flourishing progress of modern medicinal chemistry, bicyclo[1.1.1]pentylamines (BCPAs) have come to the fore as bioisosteres of arylamine motifs to reduce the concern about the risks of arylamines in bioactivity.
Topics & Concepts
FlourishingChemistryBicyclic moleculeDrugCombinatorial chemistryPharmacologyStereochemistryPsychologyMedicinePsychotherapistRadical Photochemical ReactionsCyclopropane Reaction MechanismsSynthesis and Catalytic Reactions