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Synthesis and biological evaluation of novel ligustrazine-chalcone derivatives as potential anti-triple negative breast cancer agents

Yingqi Luo, Wenhao Wu, Dailong Zha, Wenmin Zhou, Chengxu Wang, Jianan Huang, Shaobin Chen, Lihong Yu, Yuanzhi Li, Qinghui Huang, Jianye Zhang, Chao Zhang

2021Bioorganic & Medicinal Chemistry Letters27 citationsDOI

Topics & Concepts

ChalconeIn vivoChemistryCytotoxicityIn vitroCell growthPotencyApoptosisIC50Cell cycle checkpointPharmacologyCell cycleCell cultureGrowth inhibitionStereochemistryBiochemistryBiologyBiotechnologyGeneticsSynthesis and biological activityHER2/EGFR in Cancer ResearchBioactive Compounds and Antitumor Agents
Synthesis and biological evaluation of novel ligustrazine-chalcone derivatives as potential anti-triple negative breast cancer agents | Litcius