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Extracorporeal liver cross-circulation using transgenic xenogeneic pig livers with brain-dead human decedents

Abraham Shaked, Alex Sagar, Kim Olthoff, Peter L. Abt, Emily A. Vail, Niels D. Martin, Charles S. Abrams, Rick D. Hasz, Christine Radolovic, Shannon Kaminski, Bao‐Li Loza, James F. Markmann, Susan C. Low, Mike Curtis, Leanne Lanieri, Kirsten G. Swenson, Gregory T. Everson, David A. Wagner, Mohamed A. Elzawahry, John Fallon, Syed Hussain Abbas, Danielle Fortuna, Emma E. Furth, K. Rajender Reddy, Peter P. Reese, Peter Friend

2026Nature Medicine7 citationsDOI

Topics & Concepts

MedicineXenotransplantationExtracorporealLiver transplantationImmunosuppressionHepatectomyImmune systemBioartificial liver deviceHuman liverTransgeneAllotransplantationPig liverPathologyHemoperfusionImmunoadsorptionInternal medicineLiver parenchymaLiver regenerationTransplantationMiniature swineGenetically modified mouseImmunologyLiver diseaseLiver dysfunctionHepatocyteParenchymaGastroenterologyFatty liverAntibodyXenotransplantation and immune responseOrgan Transplantation Techniques and OutcomesLiver physiology and pathology
Extracorporeal liver cross-circulation using transgenic xenogeneic pig livers with brain-dead human decedents | Litcius