The synergistic effect of epigallocatechin-3-gallate and quercetin co-loaded hydrogel beads on inflammatory bowel disease
Miao Hu, Yuyang Huang, Xiaoqian Du, Guannan Liu, Baokun Qi, Yang Li
Abstract
The synergistic effect of epigallocatechin-3-gallate (E) and quercetin (Q) enhances the therapeutic efficacy on related diseases; however, the instability and lower bioavailability of E and Q limited their application.
Topics & Concepts
ChemistryInflammatory bowel diseaseBioavailabilityTLR4QuercetinGallateEpigallocatechin gallatePharmacologyTumor necrosis factor alphaProinflammatory cytokineInflammationSignal transductionBiochemistryImmunologyInternal medicineMedicinePolyphenolDiseaseNuclear chemistryAntioxidantTea Polyphenols and EffectsInflammatory Bowel DiseaseAdvanced Glycation End Products research