Enzyme‐Encapsulated DNA Hydrogel for Highly Efficient Electrochemical Sensing Glucose
Ruijin Zeng, Zhenliang Huang, Yankun Wang, Dianping Tang
Abstract
Abstract An innovative bioetching photoelectrochemical (PEC) mode was developed by using enzyme‐encapsulated DNA hydrogel for high‐precision quantification of glucose, using In 2 O 3 −CdS nanocomposite as a photoactive matrix. In a proof‐of‐concept study, horseradish peroxidase and glucose oxidase were encapsulated in situ in DNA hydrogel to initiate enzymatic bioetching of CdS nanoparticles in the presence of target glucose. The bioetching reaction of CdS inhibits the electron transfer efficiency of In 2 O 3 and CdS, which causes a change in photocurrent intensity and thus provides a powerful bioetching PEC strategy with enzyme‐encapsulated DNA hydrogel.
Topics & Concepts
Glucose oxidaseHorseradish peroxidasePhotocurrentChemistryPeroxidaseDNABiosensorNanocompositeEnzymeElectrochemistryChemical engineeringElectron transferImmobilized enzymeMaterials scienceNanotechnologyCombinatorial chemistryBiochemistryPhotochemistryElectrodeOptoelectronicsPhysical chemistryEngineeringAdvanced biosensing and bioanalysis techniquesBiosensors and Analytical DetectionAdvanced Nanomaterials in Catalysis