Asymmetric Synthesis and Biological Screening of Quinoxaline-Containing Synthetic Lipoxin A<sub>4</sub> Mimetics (QNX-sLXms)
Monica de Gaetano, Catherine Tighe, Kevin Gahan, Andrea Zanetti, Jianmin Chen, Justine Newson, Antonino Cacace, Mariam Marai, Andrew Gaffney, Eoin Brennan, Phillip Kantharidis, Mark E. Cooper, Xavier Leroy, Mauro Perretti, Derek W. Gilroy, Catherine Godson, Patrick J. Guiry
Abstract
in the context of novel inflammatory regulators.
Topics & Concepts
ChemistryInflammationQuinoxalineIn vivoLipopolysaccharideIn vitroPharmacologyReceptorContext (archaeology)Tumor necrosis factor alphaLipoxinBiochemistryImmunologyBiologyOrganic chemistryBiotechnologyPaleontologyinterferon and immune responsesInflammatory mediators and NSAID effectsFatty Acid Research and Health