Healthcare workers hospitalized due to COVID-19 have no higher risk of death than general population. Data from the Spanish SEMI-COVID-19 Registry
Jesús Díez‐Manglano, Marta Nataya Solís-Marquínez, Andrea García, N. Alcalá-Rivera, Irene Maderuelo Riesco, Martín Gericó Aseguinolaza, José Luis Beato Pérez, Manuel Méndez‐Bailón, Ane-Elbire Labirua-Iturburu Ruiz, Miriam García Gómez, Carmen Martínez Cilleros, Paula María Pesqueira Fontán, Lucy Abella Vázquez, Julio César Blázquez Encinar, Ramón Boixeda, Ricardo Gil Sánchez, Andres Fernandez, José Loureiro-Amigo, Joaquín Escobar Sevilla, Marcos Guzmán García, María Dolores Martín Escalante, Jeffrey Óskar Magallanes Gamboa, Ángel Luis Martínez González, Carlos Lumbreras, Juan Miguel Antón Santos, for the SEMI-COVID-19 Network
Abstract
AIM: To determine whether healthcare workers (HCW) hospitalized in Spain due to COVID-19 have a worse prognosis than non-healthcare workers (NHCW). METHODS: Observational cohort study based on the SEMI-COVID-19 Registry, a nationwide registry that collects sociodemographic, clinical, laboratory, and treatment data on patients hospitalised with COVID-19 in Spain. Patients aged 20-65 years were selected. A multivariate logistic regression model was performed to identify factors associated with mortality. RESULTS: As of 22 May 2020, 4393 patients were included, of whom 419 (9.5%) were HCW. Median (interquartile range) age of HCW was 52 (15) years and 62.4% were women. Prevalence of comorbidities and severe radiological findings upon admission were less frequent in HCW. There were no difference in need of respiratory support and admission to intensive care unit, but occurrence of sepsis and in-hospital mortality was lower in HCW (1.7% vs. 3.9%; p = 0.024 and 0.7% vs. 4.8%; p<0.001 respectively). Age, male sex and comorbidity, were independently associated with higher in-hospital mortality and healthcare working with lower mortality (OR 0.211, 95%CI 0.067-0.667, p = 0.008). 30-days survival was higher in HCW (0.968 vs. 0.851 p<0.001). CONCLUSIONS: Hospitalized COVID-19 HCW had fewer comorbidities and a better prognosis than NHCW. Our results suggest that professional exposure to COVID-19 in HCW does not carry more clinical severity nor mortality.