Defining Galactomannan Positivity in the Updated EORTC/MSGERC Consensus Definitions of Invasive Fungal Diseases
Toine Mercier, Elio Castagnola, Kieren A. Marr, L. Joseph Wheat, Paul E. Verweij, Johan Maertens
Abstract
The consensus definitions of invasive fungal diseases from the EORTC/MSGERC were recently revised and updated. They now include consensus cutoff values for the galactomannan test that support the diagnosis of probable invasive aspergillosis. In this supplement article, we provide a rationale for these proposed thresholds based on the test's characteristics and performance in different patient populations and in different specimen types.
Topics & Concepts
GalactomannanMedicineConsensus conferenceAspergillosisTest (biology)Intensive care medicineImmunologyInternal medicineBiologyEcologyAntifungal resistance and susceptibilityFungal Infections and StudiesPlant Pathogens and Fungal Diseases