Litcius/Paper detail

Biotinylated magnetic molecularly imprinted polymer nanoparticles for cancer cell targeting and controlled drug delivery

Maria Nerantzaki, Aude Michel, Laurence Petit, Maylis Garnier, Christine Ménager, Nébéwia Griffete

2022Chemical Communications28 citationsDOIOpen Access PDF

Abstract

Here, multivalent functions have been successfully integrated on a single core-shell type nanostructure, for remote-controlled and receptor-targeted intracellular delivery of doxorubicin (DOX) to breast cancer cells that overexpress biotin receptors.

Topics & Concepts

BiotinylationMolecularly imprinted polymerDoxorubicinTargeted drug deliveryDrug deliveryCancer cellNanotechnologyNanoparticleMagnetic nanoparticlesIntracellularBiotinChemistryMolecular imprintingReceptorBiophysicsMaterials scienceCancerBiochemistrySelectivityMedicineChemotherapyBiologyCatalysisSurgeryInternal medicineBiotin and Related StudiesAdvanced biosensing and bioanalysis techniquesMass Spectrometry Techniques and Applications