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Application of pH-salt dual gradient elution in purifying a WuXiBody-based bispecific antibody by MMC ImpRes mixed-mode chromatography

Yan Wan, Yumeng Wang, Ting Zhang, Shengwei Zhang, Ying Wang, Yifeng Li

2021Protein Expression and Purification13 citationsDOI

Topics & Concepts

ElutionChemistryChromatographySalt (chemistry)Gradient elutionDownstream processingResolution (logic)High-performance liquid chromatographyComputer scienceOrganic chemistryArtificial intelligenceMonoclonal and Polyclonal Antibodies ResearchGlycosylation and Glycoproteins ResearchProtein purification and stability
Application of pH-salt dual gradient elution in purifying a WuXiBody-based bispecific antibody by MMC ImpRes mixed-mode chromatography | Litcius