Litcius/Paper detail

Simultaneous Detection of Morphine and Diclofenac Using Graphene Nanoribbon Modified Screen-Printed Electrode

Peyman Mohamadzadeh Jahani, Sayed Zia Mohammadi, Ali Khodabakhshzadeh, Joo Hwan, Mehdi Shahedi Asl, Mohammadreza Shokouhimehr, Kaiqiang Zhang, Quyet Van Le, Wanxi Peng

2020International Journal of Electrochemical Science32 citationsDOIOpen Access PDF

Abstract

The graphene nanoribbon modified screen printed electrode (G/SPE) has been produced to determine morphine and diclofenac via differential pulse voltammetric, cyclic voltammetric, and chronoamperometry. Graphene nanoribbon shows great selectivity and sensitivity in determining morphine and diclofenac. The impact of scan rates has been explored. Findings showed that it is diffusion-controlled. The impact of morphine concentrations has been investigated in ranges of 0.07-600.0 μM. Determination limit for morphine has been 20.0 nM. In general, an easy experimental method for manufacturing graphene oxide nanoribbon has been suggested that takes advantage of selectivity, reproducibility, and sensitivity toward electro-active specimens, as well as biological matrices.

Topics & Concepts

GrapheneElectrodeDiclofenacMaterials scienceMorphineNanotechnologyOptoelectronicsBiomedical engineeringAnesthesiaMedicineChemistryPhysical chemistryElectrochemical sensors and biosensorsPharmacological Effects and AssaysAnalytical Methods in Pharmaceuticals