Cardiac Troponin I Is an Independent Predictor for Mortality in Hospitalized Patients With COVID-19
Shao-Fang Nie, Miao Yu, Tian Xie, Fen Yang, Hong-Bo Wang, Zhao-Hui Wang, Ming Li, Xing-Li Gao, Bing-Jie Lv, Shijia Wang, Xiao-Bo Zhang, Shao-Lin He, Zhi-Hua Qiu, Yu-Hua Liao, Zihua Zhou, Xiang Cheng
Abstract
heart injuries ◼ hospital mortality ◼ patient outcome assessment ◼ troponin I S ince December 2019, coronavirus disease 2019 (COVID-19) has caused a global pandemic with thousands of pneumonia-related deaths. 1 Recently, Wang et al 2 reported the existence of myocardial injury in 7.2% of all patients with COVID-19 and in 22.2% of patients admitted to the intensive care unit versus only 2.0% patients not treated in the intensive care unit.Thus, we hypothesized that cardiac troponin I (cTNI), an established biomarker of cardiac injury, may be a clinical predictor of outcomes for patients with COVID-19.Patients with laboratory-confirmed COVID-19 admitted to Union Hospital (West Campus), Huazhong University of Science and Technology from January 12 to March 12, 2020, were enrolled, and the final date of follow-up was March 20, 2020.This study was